Progressive Strength Training in Spinal Muscular Atrophy

Study Identifier:
39995
ClinicalTrials.gov Identifier:
NCT01233817
EudraCT Identifier:
N/A
EU CT Number:
N/A
Sponsor:
University of Utah
Study Complete

Study Details

Medical Condition
  • All Spinal Muscular Atrophies
Study Drug
    Date
    Jun 2010 - Jun 2013
    Patient Requirements
    Sex: Female & Male
    Age: 5 - 21 Years
    Requirements Information
    Inclusion and Exclusion Criteria
    Inclusion Criteria
    • age 5-21 years
    • diagnosis of SMA type II or III
    • at least antigravity strength in elbow flexors
    • ability to follow commands and stay on task
    • place of residence within a 60-minute or 60-mile drive of the University of Utah
    Exclusion Criteria
    • planned surgery or out-of-town trips during the proposed intervention period
    • inability to travel to study center for testing
    • neurological diagnosis other than SMA

    Protocol Summary

    The proposed feasibility study is necessary to test if children and young adults will participate in and adhere to a 12-week, home-based, supervised progressive strength training exercise program and to obtain preliminary data that will subsequently allow us to determine the safety and impact of strength training in spinal muscular atrophy. Our pilot study will address 3 aims: (1) Ascertain the feasibility of, and potential barriers to, participation in and adherence to a 12-week home-based, supervised, progressive strength training exercise program in children and young adults aged 5-21 years with SMA types II and III; (2) Determine the safety and tolerability of progressive strength training in a pilot study sample of children and young adults with SMA types II and III; and (3) Determine candidate outcome measures.

    Trial Locations

    Location
    Status
    Location
    University of Utah
    Salt Lake City, Utah, United States, 84132
    Status
    N/A

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